Sherice is the older sister of Robinson Ashe III, who meet Brandon Walsh after they literally crash into each other outside of her home, across the street from the Walshes on Hillcrest Drive. Brandon and Sherice fight and do not get along at first, but after a few interactions, begin openly flirting with each other.
Brandon and Sherice went on a date, but while they were out, her ex-boyfriend, Devo Demars, came into Beverly Hills to surprise her and got arrested by the cops because he was black. Brandon and Sherice went back to fighting, but eventually found a common ground after Brandon wrote an article on Devo's treatment.
They were last seen giving each other a playful hard time outside their respective homes as Sherice was about to go see Devo at his place of work.